DNA Cardiovascular Health Test
Family history is important when assessing your risk of cardiovascular disease, because genes can influence your risk of a heart attack. Find out if you are at risk with the DNA Cardiovascular Health Test.
- Includes genetic variants linked to lipid levels such as cholesterol and triglycerides
- Understand your risk and make changes to protect your heart health
Cardiovascular disease refers to a large spectrum of disorders, many of which involve narrowed or blocked blood vessels, leading to chest pain (angina), heart attacks and strokes.
Cardiovascular diseases are the leading cause of death amounting to over 30% of all deaths worldwide. Lifestyle choices, such as physical inactivity, unhealthy eating habits and smoking, can all increase the risk of heart problems. But there are also “hidden” factors (i.e. certain genetic variants) that can also predispose to heart attacks.
A simple mouth swab is all we need to find out whether you have inherited DNA changes that affect the health of your heart.
Cardiovascular disease has been linked to a number of genetic variants. While some variants can increase the risk of cardiovascular disease, others can offer a protective effect.
Here is a list of tested variants along with their effects:
|ANGPTL4, APOA5, FADS1, GALNT2, HNF4A, LIPG, MMAB||Reduced levels of “good” HDL-cholesterol|
|CETP, LCAT, LIPC, LPL||Elevated levels of “good” HDL-cholesterol|
|APOB, FADS1, LDLR, NCAN, PCSK9, SORT1, SUGP1||Reduced levels of “bad” LDL-cholesterol|
|HMGCR, HNF1A, TRIB1||Elevated levels of “bad” LDL-cholesterol|
|LPA||Elevated levels of lipoprotein(a)|
|CRP, GCKR||Elevated levels of C-reactive protein (CRP)|
|APOA5, FADS1, GALNT2, GCKR, NOS3, TRIB1||Elevated levels of triglycerides|
|ANGPTL3, LPL, MLXIPL, NCAN||Reduced levels of triglycerides|
|9p21||Decreased control of cell proliferation|
FACTORS THAT AFFECT YOUR CARDIOVASCULAR HEALTH
- Cholesterol is a fat-like substance that our body produces and we get from certain foods. It travels around our body in two types of lipoproteins: HDL and LDL. Low levels of “good” HDL-cholesterol or high levels of “bad” LDL-cholesterol can cause cholesterol to build up in our arteries, leading to narrowed or blocked blood vessels.
- Triglycerides are obtained from the digestion and breakdown of fats in food. They make up the majority of fat deposits in our body. Excessive triglyceride levels contribute to obesity and heart disease.
- C-reactive protein (CRP) is a substance produced by the liver that increases during an inflammatory response. Elevated CRP levels can lead to heart disease.
- Lipoprotein(a) is a type of lipoprotein similar to “bad” LDL. It is rich in cholesterol, and excess levels increase the risk of cardiovascular disease.
HOW IT WORKS
Step 1: Order test kit online
Step 2: Collect DNA sample using a painless mouth swab, and mail to the lab in the provided return envelope
Step 3: Receive your results online